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Brought to you by the Resident and Fellow Section of Neurology®.
June 14, 2011
Numb chin syndrome (NCS), or mental neuropathy, is a rare and potentially ominous sensory neuropathy characterized by unilateral hypoesthesia or paresthesias over the lower lip, chin and occasionally gingival mucosa. The mandibular branch (V3) of the trigeminal nerve exits the skull through the foramen ovale and divides into an anterior motor trunk and a posterior sensory trunk, the inferior alveolar nerve. It then exits the mental foramen in the mandible as the mental nerve. NCS may be a sign of occult malignancy. The most common neoplastic causes of NCS are breast cancer, and non-Hodgkin lymphoma.
Yuan Fan, MD, PhD
Disclosure: Dr. Fan reports no disclosures.
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