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“Hitting the Mattress with MS” (January/February 2009) should be mandatory reading for anyone who has multiple sclerosis (MS) or lives with someone who does. As an MS patient, the explanation of the problems around sleeping was right on. I suffer terribly at night with spasms, pain, and tingling and have lost the ability to turn over lying down. Plus, I wake up approximately every two hours having to go to the bathroom.