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Brought to you by the Resident and Fellow Section of Neurology®.
July 11, 2011
The presence of vertical gaze palsy in the context of parkinsonism is highly suggestive of progressive supranuclear palsy (PSP). There are, however, other clinical entities that may present with this clinical sign such as fronto-temporal dementia , corticobasal degeneration, dementia with Lewy Body, Kufor-Rakeb syndrome (PARK-9) and Niemann-Pick type C. Other rarer causes include Gaucher’s disease, Whipple’s disease, syphilis and some clinical presentations of Creutzfeldt-Jakob disease.
Dr. Martin Grecco
Disclosure: Dr. Grecco received a scholarship from the UCL Institute of Neurology in London.
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