E-Pearl of the Week: The 'Hot and Dry Foot' as a Sign of Cancer

May 3, 2011

Share:

Interested in submitting an e-Pearl? Click here!

Brought to you by the Resident and Fellow Section of Neurology®.

May 3, 2011

The 'Hot and Dry Foot' as a Sign of Cancer


Lumbosacral plexopathy is a serious and often disabling neurologic complication in patients with advanced cancer. It was the initial presentation of cancer in 15% of patients in a series of 85 patients with neoplastic lumbosacral plexopathy.

A unilateral hot and dry foot as a patient complaint should trigger consideration of a neoplastic lumbosacral plexopathy. The symptom is a manifestation of interruption of postganglionic sympathetic innervation of the foot.

References

  1. Jaeckle KA, Young DF, Foley KM. The natural history of lumbosacral plexopathy in cancer. Neurology 1985; 35:358-15.
  2. Dalmau J, Graus F, Marco M. 'Hot and dry foot' as initial manifestation of a neoplastic lumbosacral plexopathy. Neurology 1989; 39: 871-872.

Submitted by:
Hani Kushlaf, M.B., B.Ch.
Dept of Neurology Mayo Clinic

Disclosure: Dr. Kushlaf reports no disclosures.

For more clinical pearls and other articles of interest to neurology trainees, visit www.neurology.org and click on the link to the Resident and Fellow Pages.

Click here to listen to this week's Neurology® Podcast.