What is Burning Mouth Syndrome?

December 15, 2010


E-Pearl of the Week

Brought to you by the Resident and Fellow Section of the journal Neurology®.

November 29, 2010

Burning Mouth Syndrome

Burning Mouth Syndrome (BMS) is a chronic orofacial pain syndrome characterized by a burning sensation of oral mucosa and xerostomia without a demonstrable dental or medical cause. It is most prevalent in postmenopausal women. Although usually constant, the pain may increase during the day and decrease with mastication. Clonazepam tablets dissolved in the mouth are often effective. Benzodiazapines, anticonvulsants, tricyclic antidepressants, serotonin reuptake inhibitors, antioxidants, capsaicin, and dopamine agonists may also be used to treat BMS.


1. Headache Classification Committee of the International Headache Society. Classification and diagnostic criteria for headache disorders, cranial neuralgias and facial pain. Second edition. Cephalagia 2004; 24(Suppl 1): 1-160 2. Speciali JG, Stuginski-Barbosa J. Burning Mouth Syndrome. Current Pain and Headache Reports 2008; 12:279-284

Submitted by Larry Charleston IV, M.D.

Disclosure: Dr. Charleston reports no disclosures.

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