Basic Science Resident Curriculum Featured Saturday, April 25

April 8, 2009


Two half-day programs at the 2009 Annual Meeting will focus on aspects of the basic sciences on which clinical neurology is founded. The curriculum is primarily intended to help neurology residents learn important building blocks of the discipline, as detailed in the Neurology Residency Review Committee (RRC) program requirements for residency education in neurology.

Offered on Saturday, April 25, on the first day of the Annual Meeting, the topics for this year's curriculum are Neurogenetics and Neurometabolic Disorders. A fee will be charged for each course, and they are open to residents as well as other interested attendees.

    1AC.001 Resident Basic Science I: Neurogenetics
    9:00 a.m–12:45 p.m.
    Director: Katherine Mathews, MD

    Neurogenetics is an integral part of all facets of neurology. Practitioners and researchers must be familiar with the mechanisms of genetic disorders in order to provide the best quality care to patients and to advance the field. Discussions will include Mendelian and non-Mendelian inheritance, chromosomal function and dysfunction, mechanisms of DNA maintenance, repair, transcription, and translation, with examples relevant to clinical practice.

    Participants should be familiar with the basic mechanisms of inheritance, maintenance, and expression of the genome and effects of epigenetic factors; and will recognize features suggestive of neurogenetic disorders, and understand the principles of diagnosis and management.

    1PC.001 Resident Basic Science II: Neurometabolic Disorders
    2:15 p.m.–6:00 p.m.
    Director: Marc Patterson, MD, FAAN

    Neurometabolic disorders, inborn errors of metabolism affecting the nervous system, are individually rare but collectively common. Advances in newborn screening and other diagnostic techniques have revealed that atypical and late-onset presentations of these diseases may explain a significant number of cases of otherwise undiagnosed neurologic disease at all ages. Faculty will review the basic science of the major families of neurometabolic diseases and relate this to clinical presentations, pathophysiology, and rational therapies for these disorders.

    Participants should be familiar with the basic metabolic pathways that influence nervous system function and the pathophysiology of diseases of these pathways, and will be able to use this information to formulate a rational approach to the diagnosis and management of neurometabolic diseases.

Read more about the Basic Science Resident Curriculum.