Interested in submitting an e–Pearl? Click here!
Brought to you by the Resident and Fellow Section of Neurology®.
July 18, 2012
Head Size in Normal Pressure Hydrocephalus
Idiopathic normal pressure hydrocephalus (iNPH) is characterized by enlarged ventricular size, often increased cerebrospinal fluid outflow resistance and normal intracranial pressure. Ten to twenty percent of patients with iNPH –across both genders - have a head circumferences above the 98th percentile compared to normal controls. Consequently, while the mechanism producing NPH in most patients is unknown, it has been suggested that a proportion of patients with iNPH may have congenital hydrocephalus which decompensates and becomes symptomatic in later adult life. It is not known whether head size predicts treatment response in NPH, and the selection of appropriate candidates for invasive shunt procedures remains challenging.
Read more about NPH and the effects of CSF drainage on ventricular size in NPH in this week’s issue of Neurology.
Submitted by: Jennifer E. Fugate, DO
Disclosures: Dr. Fugate serves on the editorial team for the Neurology Resident and Fellow Section.
For more clinical pearls and other articles of interest to neurology trainees, visit www.neurology.org and click on the link to the Resident and Fellow Pages. Click here to visit the E-Pearl of the Week Archive.Click here to listen to this week’s Neurology® Podcast.