Search for specific clinical trials that are underway using the keyword search below.
Patient support groups also offer information about clinical trials.
ClinicalTrials.gov Search
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NINDS Disorders is an index of neurological conditions provided by the National Institute of Neurological Disorders and Stroke. This valuable tool offers detailed descriptions, facts on treatment and prognosis, and patient organization contact information for over 500 identified neurological disorders.
Cerebral Hypoxia
Cerebral hypoxia refers to a condition in which there is a decrease of oxygen supply to the brain even though there is adequate blood flow. Drowning, strangling, choking, suffocation, cardiac arrest, head trauma, carbon monoxide poisoning, and complications of general anesthesia can create conditions that can lead to cerebral hypoxia. Symptoms of mild cerebral hypoxia include inattentiveness, poor judgment, memory loss, and a decrease in motor coordination. Brain cells are extremely sensitive to oxygen deprivation and can begin to die within five minutes after oxygen supply has been cut off. When hypoxia lasts for longer periods of time, it can cause coma, seizures, and even brain death. In brain death, there is no measurable activity in the brain, although cardiovascular function is preserved. Life support is required for respiration.
Treatment
Treatment depends on the underlying cause of the hypoxia, but basic life-support systems have to be put in place: mechanical ventilation to secure the airway; fluids, blood products, or medications to support blood pressure and heart rate; and medications to suppress seizures.
Prognosis
Recovery depends on how long the brain has been deprived of oxygen and how much brain damage has occurred, although carbon monoxide poisoning can cause brain damage days to weeks after the event. Most people who make a full recovery have only been briefly unconscious. The longer someone is unconscious, the higher the chances of death or brain death and the lower the chances of a meaningful recovery. During recovery, psychological and neurological abnormalities such as amnesia, personality regression, hallucinations, memory loss, and muscle spasms and twitches may appear, persist, and then resolve.
Research
The NINDS supports and conducts studies aimed at understanding neurological conditions that can damage the brain, such as cerebral hypoxia. The goals of these studies are to find ways to prevent and treat these conditions.
View a list of studies currently seeking patients.
View more studies on this condition.
Organizations
Brain Injury Association of America, Inc.
Non-profit organization dedicated to people with brain injury and their families. Offers research, education, and advocacy programs through a national office, network of state affiliates, support groups, and a helpline.
1608 Spring Hill Rd
Suite 110
Suite 110
Vienna, VA 22182
Tel: 703-761-0750
800-444-6443
Fax: 703-761-0755
National Rehabilitation Information Center (NARIC)
8201 Corporate Drive
Suite 600
Suite 600
Landover, MD 20785
Tel: 301-459-5900/301-459-5984 (TTY)
800-346-2742
Fax: 301-562-2401
Brain Injury Resource Center
Non-profit clearinghouse founded and operated by head injury activists. Offers information, discussion groups, programs for building advocacy and self-care skills, and referrals to additional information and resources.
P.O.Box 84151
Seattle, WA 98124
Tel: 206-621-8558
Fax: 206-329-4355
Brain Trauma Foundation
Nationwide organization devoted to improving the outcome of traumatic brain injury patients. Focuses on the acute phase of traumatic brain injury (TBI) and methods to improve chances of a meaningful recovery. The Foundation works to improve the care of TBI patients from the scene of injury to the emergency room and ICU through guidelines development, professional education, quality improvement, and clinical research.
7 World Trade Center
250 Greenwich Street
34th Floor
34th Floor
New York, NY 10017
Tel: 212-772-0608
Fax: 212-772-0357
Easter Seals
Provides services to help children and adults with disabilities and/or special needs as well as support to their families. Supports the National AgrAbility Project, a program for farmers, ranchers, and farm workers with disabilities.
233 South Wacker Drive
Suite 2400
Suite 2400
Chicago, IL 60606
Tel: 312-726-6200
800-221-6827
Fax: 312-726-1494